Permanently Discontinued

PREMARIN VAGINAL CREAM

PFIZER CANADA ULC

This is a national manufacturer shortage report. It does not confirm whether the product is unavailable at your local pharmacy — call ahead or ask your pharmacist.

Quick answers

Is PREMARIN VAGINAL CREAM discontinued in Canada?

Yes. The manufacturer has reported to Health Canada that PREMARIN VAGINAL CREAM 0.625MG has been permanently discontinued (last updated November 4, 2026). It is not expected to come back, so talk to your pharmacist or doctor about an alternative.

Why is PREMARIN VAGINAL CREAM not available?

The reason the manufacturer reported: Business reasons.

Can I still get this?Check with your pharmacist — only products with a different form or route found

StatusPermanently Discontinued

Same-ingredient products on file1 product · 0 same form & route

Affected strength0.625MG

Report last updated2026-11-04

Checked by MedShort2026-11-12

Other Products Containing the Same Active Ingredient

These are other Health Canada-approved human drug products containing the same active ingredient, not currently reported in shortage. Strength, dosage form, and route can still differ — ask your pharmacist whether any of these are appropriate for you. This isn't a guarantee of current stock.

Other Products

PREMARIN

PFIZER CANADA ULC

0.625MG · DIN 02414686

Same strengthDifferent dosage formDifferent routeNo current shortage

Compare these two →

What this means

Does this mean I need to switch medications right away?

Not necessarily right away, but this product will not be returning to the market.

What should I do?

Talk to your pharmacist or prescriber about your options well before your current supply runs out.

DIN

02043440

Strength

0.625MG

Dosage Form

CREAM

Route

VAGINAL

Active Ingredient

CONJUGATED ESTROGENS

Tier

Unrated

Last Updated

2026-11-04

Reason for Shortage

Business reasons

Source

View original report on healthproductshortages.ca ↗

Past Reports for This Drug

PREMARIN VAGINAL CREAM has 3 shortage/discontinuation reports on file — this is one of them.

2026-11-03

Resolved

Disruption of the manufacture of the drug.

2018-10-01

Permanently Discontinued

Business reasons

Other Products from PFIZER CANADA ULC

Other Health Canada-approved products made by the same manufacturer — not necessarily related to this shortage, and not necessarily in shortage themselves.

40MG · DIN 02511053

40MG · DIN 02511045

20MG · DIN 02511061

DIN 02544040

5MG · DIN 01947664

10MG · DIN 01947672